Alimta Injection 500 Mg 1 Vial ^

How it works

Alimta Injection 500 mg 1 Vial ^ works by blocking the action of a certain substance in the body that may help cancer cells multiply.

Side effects
Major & minor side effects for Alimta Injection 500 mg 1 Vial ^
Low WBC and Platelet count severe
Fever and chills severe
Mouth ulcers severe
Nausea and Vomiting severe
Skin rash severe
Decreased urine output severe
Blood in urine and stools severe
Diarrhea
Cough
Hair loss
Change in mood
Uses of Alimta Injection 500 mg 1 Vial ^
What is it prescribed for?
Malignant Pleural MesotheliomaThis medicine is used in the treatment of cancer that develops in the thin layer of tissue surrounding the lungs (Pleura).
Non-Small Cell Lung CancerThis medicine is used in the treatment of cancer that affects the lungs.
Concerns
Frequently asked questions
Onset of action

The peak effect of this medicine can be observed immediately after intravenous injection.

Duration of Effect

The effect of this medicine lasts for an average duration of 6 to 9 hours.

Safe with Alchohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendency has reported.

Usage in pregnancy?

This medicine is not recommended for pregnant women.

Usage while breast-feeding?

This medicine is not recommended in breastfeeding women.

When not to use?
Allergy

Not recommended in patients with known allergy to Alimta Injection 500 mg 1 Vial ^ .

Warnings
Warnings for special population
Pregnancy

This medicine is not recommended for pregnant women.

Breast-feeding

This medicine is not recommended in breastfeeding women.

General Warnings
Premedication

Before starting the treatment, premedication with oral folic acid and intramuscular vitamin B12 is recommended to reduce the severity of hematologic and gastrointestinal toxicity.

Blood cell count

This medicine is known to decrease the neutrophils and platelets count. Blood reports should be obtained before initiating the treatment. The dose of this medicine should be reduced based on the absolute neutrophil count and platelet count.

Skin reactions

This medicine may cause severe skin reactions. To reduce the severity of these reactions, corticosteroids like dexamethasone should be given before, during and after [post-title] administration.

Infections

The patients receiving this medicine have a higher chance of developing infections. Hold the chemotherapy and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

Dosage
Missed Dose

It is advised not to miss any dose. If you miss any dose, you should contact your doctor immediately.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines

Clozapine severe
Live attenuated vaccines and related products severe
Fluoroquinolone antibiotics moderate

Disease interactions

moderateThis medicine should be used with caution in patients with the kidney disease. Close monitoring of kidney function is necessary. It is not recommended in patients with Creatinine Clearance less than 45 ml/min.
General Instructions

This medicine should be used with caution in patients with the kidney disease. Close monitoring of kidney function is necessary. It is not recommended in patients with Creatinine Clearance less than 45 ml/min.

Other details
Can be taken with or without food, as advised by your doctor
To be taken as instructed by doctor
Does not cause sleepiness
References
medlineplus.gov – Pemetrexed [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a607043.html [cited 10/8/2020]. 2020

Additional Information:

How to use Alimta Injection 500 mg 1 Vial ^

Administered as an IV infusion over 10 min. Pemetrexed is compatible with standard polyvinyl chloride (PVC) administration sets and IV solution bags.
Reconstitution: Reconstitute each 100 mg vial with 4.2 mL of 0.9% NaCl (preservative free). Reconstitute 500 mg vials with 20 mL of 0.9% NaCl (preservative free). Reconstitution of either size vial gives a solution containing pemetrexed 25 mg/mL. Gently swirl each vial until the powder is completely dissolved. Further dilution is required. An appropriate quantity of the reconstituted pemetrexed solution must be further diluted into a solution of 0.9% NaCl (preservative free), so that the total volume of solution is 100 mL.
Compatibility: Stable in NS. Incompatible with diluents containing calcium, including Ringer’s lactate injection and Ringer’s injection.
Stability: Store at 25°C (77°F); excursions are permitted between 15°C-30°C (59°F-86°F). Reconstituted and infusion solutions are stable for up to 24 hours following initial reconstitution when stored refrigerated between 2°C-8°C (36°F-46°F) or at 25°C (77°F); excursions are permitted to 15°C-30°C (59°F-86°F). Discard unused portion.

what are the adverse effects of Alimta Injection 500 mg 1 Vial ^?

Blood dyscrasias, conjunctivitis, GI upset, dehydration, fatigue, neuropathy, skin reactions, alopecia, pyrexia, renal failure, chest pain, allergic reactions.

What happens if I miss a dose of Alimta Injection 500 mg 1 Vial ^?

Malignant Pleural Mesothelioma: Adults: 500 mg/m² IV over 10 min on Day 1 of each 21-day cycle with cisplatin 75 mg/m² infused over 2 hr beginning 30 min after pemetrexed.

One of the following licensed pharmacy from the nearest location will deliver Alimta Injection 500 mg 1 Vial ^. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.