Iressa 250 mg

• Potent and selective small-molecule inhibitor of the kinase activity of wild-type and certain activating mutations of EGFR, resulting in inhibition of EGFR autophosphorylation and inhibition of EGFR signaling.

• Inhibition of the EGFR tyrosine kinase results in inhibition of critical mitogenic and antiapoptotic signals involved in proliferation, growth, metastasis, angiogenesis, and response to chemotherapy and/or

radiation therapy.