Description
Ofev 150 mg Capsules (Nintedanib)
Nintedanib 150 mg is one of the few medicines proven to slow lung scarring in people with pulmonary fibrosis. OnlineDawai supplies original Ofev 150mg capsules in Pakistan, made by Boehringer Ingelheim, in packs of 60 capsules. That is a full month’s supply at the usual dose. Check this page for the current price and availability.
Ofev contains nintedanib, a tyrosine kinase inhibitor that helps slow the progression of certain chronic fibrosing lung diseases.
Key Benefits of Ofev 150 mg
- Slows lung disease progression: Helps slow the decline in lung function in adults with idiopathic pulmonary fibrosis (IPF).
- Supports lung function management: Helps slow disease progression in selected patients with progressive fibrosing interstitial lung diseases.
- Treats systemic sclerosis-associated lung disease: Helps slow the rate of decline in lung function in adults with systemic sclerosis-associated interstitial lung disease (SSc-ILD).
- Targets fibrosis-related pathways: Works by inhibiting specific enzymes involved in processes that contribute to fibrosis.
- Supports long-term disease management: May help eligible patients manage the progression of their condition as part of a specialist-directed treatment plan.
How It Works
- Pulmonary fibrosis is a condition in which the lung tissue becomes thick and scarred over time.
- This makes it harder for oxygen to pass into the blood, leading to breathlessness, a dry cough and tiredness.
- Nintedanib is a tyrosine kinase inhibitor that blocks several signals involved in scar formation.
- It cannot reverse scarring that has already happened, but studies show it slows the decline in lung function.
- Ofev is prescribed for idiopathic pulmonary fibrosis, other progressive fibrosing interstitial lung diseases, and lung disease linked to systemic sclerosis.
- The usual dose is one 150 mg capsule twice a day, about 12 hours apart. Take the capsules with food and swallow them whole with water. Do not chew or crush them. If you miss a dose, skip it and take the next one at the usual time. Your doctor may lower the dose to 100 mg if you have side effects.
- Ofev does not cure pulmonary fibrosis or reverse existing lung scarring. Its benefits depend on the patient’s condition and response to treatment.
Dosage, Side Effects & Precautions
Ofev 150 mg Dosage and Administration:
- The appropriate dosage depends on the condition being treated, tolerability, and the prescribing specialist’s instructions.
- Usual adult dose: For many approved indications, the recommended dose is 150 mg twice daily, approximately 12 hours apart.
- How to take it: Swallow the capsules whole with water. Do not chew, crush, or open them.
- Take with food: Take each dose with food to help improve tolerability.
- Missed dose: Skip the missed dose and take the next dose at its regular scheduled time. Do not take an extra dose to make up for it.
- Dose adjustments: Your doctor may reduce the dose or temporarily interrupt treatment if significant side effects occur.
- Do not change your dose or stop treatment without consulting your specialist.
Ofev 150 mg Side Effects:
- Ofev may cause side effects that require monitoring during treatment. Common side effects include:
- Diarrhoea
- Nausea and vomiting
- Abdominal pain
- Reduced appetite
- Weight loss
Important Precautions:
- Liver problems: Nintedanib can cause liver injury. Your doctor should check liver function before treatment and regularly during therapy.
- Bleeding risk: Ofev may increase bleeding risk. Inform your doctor if you take anticoagulants or other medicines that increase bleeding.
- Gastrointestinal problems: Persistent diarrhoea or vomiting can cause dehydration. Contact your healthcare professional if symptoms are severe or do not improve.
- Pregnancy precautions: Ofev may harm an unborn baby. Women who could become pregnant should use effective contraception during treatment and for at least three months after the last dose.
- Other serious risks: Severe abdominal pain or signs of significant bleeding require prompt medical assessment.
- Report persistent or severe side effects to your doctor. Do not start anti-diarrhoea medicines without checking with your healthcare professional or pharmacist.
Frequently Asked Questions (FAQs)
1. What is Ofev 150 mg used for?
2. How often should Ofev 150 mg be taken?
3. What are the most common side effects of Ofev?
4. Does Ofev cure pulmonary fibrosis?
5. How should Ofev 150 mg capsules be stored?
Medical disclaimer: This information is for educational purposes only and does not replace professional medical advice. Ofev should be used under the supervision of a qualified healthcare professional.




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