Description
A Summarized Overview
Xeplion 150mg/1.5ml is a long-acting injectable atypical antipsychotic medication. It is designed for the maintenance and management of schizophrenia in adult patients. By slowly releasing paliperidone into the bloodstream over time, Xeplion helps maintain steady medication levels in the body without requiring daily oral doses.
Key Benefits & Uses
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Delivers long-acting symptom control to lower the risk of schizophrenia relapses.
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Injected once monthly, improving consistency for patients who struggle with taking daily medication.
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Helps reduce core symptoms of schizophrenia, such as hallucinations, delusions, disorganized speech, and social withdrawal.
Common Side Effects
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Injection site pain, redness, or mild swelling
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Drowsiness, fatigue, or sedation
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Weight gain or increased appetite
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Restlessness (akathisia) or mild muscle stiffness/tremors
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Headache or dizziness
Key Precautions
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Must be prescribed and administered under the supervision of a qualified healthcare professional or psychiatrist.
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Keep refrigerated between 2°C and 8°C during storage and transport; do not freeze.
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Patients should be monitored for blood pressure fluctuations, blood sugar changes, and involuntary muscle movement disorders (tardive dyskinesia).
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Not recommended for elderly patients with dementia-related psychosis due to an increased risk of stroke and mortality.
Frequently Asked Questions (FAQs)
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How often is Xeplion 150mg administered?
Once monthly (after the initial doctor-guided startup doses).
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Can I give this injection at home by myself?
No. It must be administered by a qualified healthcare professional into the shoulder or buttock.
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Do I need a prescription to purchase Xeplion in Pakistan?
Yes. It is an Rx-only medicine and requires a valid doctor’s prescription.
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What should I do if a dose is missed?
Contact your psychiatrist immediately to reschedule safely.
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How should Xeplion be stored during delivery?
In insulated cold-chain packaging (2°C to 8°C) away from direct heat.


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